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Science : 13 Vitamin details




    o The discovery of the vitamins was a major scientific achievement in our understanding of health and disease in 1912, Casimir Funk, who is considered the “father of vitamin thepapy” originally coined the term “Vitamin”. The mejor period of discovery began in the early nineteenth century and ended at the mid-twentieth century.


Vitamins are organic compounds that are esential in very small amounts for supporting normal physiologic function.
We Very need vitamins in our diets-chart daily , because our bodies can’t synthesize them quickly enough to meet our daily needs.
Vitamins have three characteristics :

  o   They are natural components of foods; usually present in very small amounts.
  o   They are essential for normal physiologic function (e.g growth reproduction etc)
  o   When absent from the diet, they will cause a specific deficiency.


9 WATER-SOLUBLE VITAMINS
( B1 , B2 , B3 , B5 , B6 , B9 , B12 , C , H)


1.  VITAMIN B1 (THIAMINE)
  o  Deficiency : 
        1.     Symptoms include burning feet
        2.     Weakness in extremities.
        3.     Rapid heart rate.
        4.     Swelling
        5.     Anorexia
        6.     Nausea
        7.     Fatigue, and
        8.     Gastrointestinal problems
  o  TOXICITY : Unknown
  o  SOURCE :
       1.     Sunflower seeds
       2.     Asparagus
       3.     Lettuce
       4.     Mushrooms
       5.     Black beans
       6.     Navy beans
       7.     Lentils
       8.     Spinac
       9.     Peas
      10. Pinto beans
      11.   Lima beans
      12.  Eggplant
      13.  Brussels sprouts
      14. Tomatoes
      15. Tuna
      16. Whole wheat
      17.  Soyabeans




2.   VITAMIN B2 (RIBOFLAVIN)

  o  DEFICIENCY :
     1.   Symtoms include cracks
     2.   Fissures and sores at corner of mouth and lips
     3.   Dermatitis
     4.   Conjunctivitis
     5.   Photophobia
     6.   Glossitis of tongue
     7.   Anxiety
     8.   Loss of appetite, and
     9.   Fatigue

 o  TOXICITY : Excess riboflavin may increase the risk of DNA strand breaks in the presence of chromium. High-dose riboflavin therapy will intensify urine color to a  yellow ( flavinuria) – but this is not harm.

 o  SOURCES:
    1.     Almonds
    2.     Soybeans / tempeh
    3.     Mushrooms
    4.     Spinach
    5.     Whole wheat
    6.     Yogurt
    7.     Mackerel
    8.     Eggs
    9.     Liver

3.  VITAMIN B3 (NIACIN)

  o  DEFICIENCY :
       1.     Symptoms include dermatitis
       2.     Diarrhea
       3.     Stomatitis
  o  TOXICITY: Niacin from foods is not known to cause adverse effects.Supplemental nicotinic acid may cause flushing of skin,itching,impaired glucose tolerance and gastrointestinal upset.intake of 750 mg per day for less than 3 months Or 12 Weeks can cause liver cell damage. High dose nicotinamide can cause nausea and liver toxicity.
  o  SOURCES :
1.     Mushrooms
2.     Asparagus
3.     Peanuts
4.     Brown rice
5.     Corn
6.     Green leafy vegetables
7.     Sweet potato
8.     Potato
9.     Lentil
10. Barley
11.  Carrots
12.  Almonds
13.  Celery
14.  Turnips
15.  Peaches
16. Chicken meat
17. Tuna
18.  Salmon

4.  VITAMIN B5 (PANTOTHENIC ACID)

  o  DEFICIENCY : very unlikely Only severe mainutrition may one notice tingling of feet.
  o  TOXICITY     : nausea, heartburn and diarrhea may be noticed with high dose supplements.
  o  SOURCES     :
       1.     Broccoli
       2.     Lentils
       3.     Split peas
       4.     Avocado
       5.     Whole wheat
       6.     Mushrooms
       7.   Sweet potato
       8.    Sunflower seeds
       9.  Cauliflower
      10.  Green leafy vegetables
      11.  Eggs
      12.  Squash
      13.  Strawberries
      14. Liver


5.  VITAMIN B6 (PYRIDOXINE)

  o  DEFICIENCY :
        1.     Symptoms includes chelosis
        2.     Glossitis
        3.     Stomatitis
        4.     Dermatitis (all similar to vitamin B2 deficiency)
        5.     Nervous system disorders
        6.     Sleeplessness
        7.     Confusion
        8.     Nervousness
        9.     Depression
       10.   Irritability
       11.  Interference with nerves that supply muscles and difficulties in movement of  these muscles

      12.  Anemia
      13.  Prenatal
      14.  Deprivation results in mental retardation and blood disorders for the newborn.

  o  TOXICITY     : high doses of supplemental vitamin b6 may result in painful neurological symptoms
  o  SOURCES     :
       1.     Whole wheat
       2.     Brown rice
       3.     Green leafy vegetables
       4.     Sunflower seeds
       5.     Potato
       6.     Garbanzo beans
       7.     Banana
       8.     Trout
       9.     Spinach
      10.   Tomatoes
      11.   Avocado
      12.  Walnuts
      13.  Peanut butter
      14.  Tuna
      15.  Salmon
      16.  Lima beans
      17.  Bell peppers
      18. Chicken meat

6.  VITAMIN B9 ( FOLIC-ACID)

  o  DEFICIENCY :
       1.     Onemay notice anemia (macrocytic / megaloblastic)
       2.     Sprue
       3.     Leukopenia
       4.     Thrombocytopenia
       5.     Weakness
       6.     Weight loss
       7.     Cracking and redness of tongue and mouth
       8.     Diarrhea. In pregnancy there is a risk of low birth weight and preterm delivery.


 o  TOXICITY     : Nonefrom food. Keep in mind that vitamin B12 and folic acid deficiency can both results in megaloblastic anemia. High doses of folic acid given to an individual with an undiagnosed vitamin B12 deficiency could correct megaloblastic anemia without correcting the underlying vitamin B12 deficiency.
 o  SOURCES     : 
    1.     Green leafy vegatables
    2.     Asparagues
    3.     Broccoli
    4.     Brussels sprouts
    5.     Citrus fruit
    6.     Black eyed peas
    7.     Spinach
    8.     Great northern beans
    9.     Whole grains
   10.    Baked beans
   11.   Green peas
   12.  Avocado
   13.   Peanuts
   14.    Lettuce
   15.    Tomato
   16.     Juice
   17.     Banana
   18.     Papaya
   19.    Organ meats

7.  VITAMIN B12 (COBALAMIN)

 o  DEFICIENCY :
    1.     Symptoms include pernicious anemia
    2.     Neurological problems and sprue
 o  TOXICITY     : None known from supplements or food. Only a Very small amount is absorbed via the oral route, thus the potential for toxicity is low

 o  SOURCES     : 
    1.     Fortified cereals
    2.     Liver
    3.     Trout
    4.     Salmon
    5.     Tuna
    6.     Haddock
    7.     Egg

8.  VITAMIN C (ASCORBIC ACID)

 o  DEFICIENCY :
1.     Symptoms include bruising
2.     Gum infections
3.     Lethargy
4.     Dental cavities
5.     Tissue swelling
6.     Dry hair and skin
7.     Bleeding gums
8.     Dry eyes
9.     Hair loss
10.            Joint paint
11.            Pitting edema
12.            Anemia
13.            Delayed wound healing
14.            Bone fragility
15.            Long term deficiency results in scurvy.



 o  SOURCES     : 
    1.     Guava
    2.     Bell pepper
    3.     Kiwi
    4.     Orange
    5.     Grapefruit
    6.     Strawberries
    7.     Brussels sprouts
    8.     Cantaloupe
    9.     Papaya
   10.   Broccoli
   11.  Sweet potato
   12.   Pineapple
   13.  Cauliflower
   14.  Kale
   15.   Lemon
   16. Juice
   17.  Parsley

9.  VITAMIN H ( BIOTIN)

 o  DEFICIENCY : Very rare in humans. Keep in mind that consuming raw egg whites over a long period of time can cause biotin deficiency. In Eggs whites contain the protein avidin, which binds to biotin and prevents its absorption.

 o  TOXICITY     : Not known to be toxic.

 o  SOURCES     : 
    1.     Green leafy vegetables
    2.     Most nuts
    3.     Whole grain breads
    4.     Avocado
    5.     Raspberries
    6.     Cauliflower
    7.     Carrots
    8.     Papaya
    9.     Banana
   10.  Salmon
  11.    eggs

FOUR (4) FAT-SOLUBLE VITAMINS  (A , D , E , K )

VITAMIN A (RETINOIDS)

 o  DEFICIENCY : One may notice difficulty seeing in dim light and rough/dry skin,.
 o  TOXICITY     : Hypervitaminosis A is caused by consuming excessive amounts of preformed vitamin A, not the plant carotenoids.Preformed vitamin A is rapidly asdorbed and slowly cleared from the body. Nausea , headache, fatigue, loss of appetite, dizziness, and dry skin can result. Excess intake while pregnant can cause birth defects.
 o  SOURCES     : 
    1.     Carrots
    2.     Sweet potato
    3.     Pumpkin
    4.     Green leafy vegetables
    5.     Squash
    6.     Cantaloupe
    7.     Bell pepper
    8.     Chines cabbage
    9.     Beef 
   10.  Egg
   11.   Peaches

2.  VITAMIN D ( CALCIFEROL)

o  DEFICIENCY :
1.     In children a vitamin D deficiency can result in rickets
2.     Deformed bones
3.     Retarded growth and soft teeth.
4.      in adults a vitamin D deficiency can result in osteomalacia
5.     Softened bones
6.     Spontaneous fractures and tooth decay
7.     Those at risk for deficiency include infants, elderly, dark skinned individuals
8.     Those with minimal sun exposure, fat malabsorption syndromes
9.     Inflammatory bowel diseases
10.            Kidney failure
11.            Seizure disorder
    o  TOXICITY     : Hypervitaminosis D is  not a result of sun exposure but from chronic supplementation. Excessive supplement use will elevete blood calcium levels and cause loss of appetite, nausea, vomiting, excessive thirst, excessive urination, itching, muscle weakness, joint pain and disorientation. Calcification of soft tissues can also occur.

    o  SOURCES     : 
1.     Sunlight
2.     Fortified foods
3.     Mushrooms
4.     Salmon
5.     Mackerel
6.     Sardines
7.     Tuna
8.     Eggs

3.  VITAMIN E ( TOCOPHEROL)

  o  DEFICIENCY :  Only noticed in those with severe malnutrition. However, sub-optimal intake of vitamin-E is relatively common.

  o  TOXICITY     : Minimal side effects have been noted in adults taking supplements in doses less than 2000 mg/day. There is a potential for impaired blood clotting.infants are more vulnerable.

  o  SOURCES     : 
        1.     Green leafy vegetables
        2.     Almonds
        3.     Sunflower seeds
        4.     Olivers
        5.     Blueberries
        6.     Most nuts
        7.     Most seeds
        8.     Tomatoes
        9.     Avocado

4.  VITAMIN E ( TOCOPHEROL)

  o  DEFICIENCY : Tendencyto bleed or hemorrhage and anemia.
  o  TOXICITY     : May interfere with glutathione. No known toxicity with high doses.
  o  SOURCES     :
1.     Broccoli
2.     Green leafy vegetables
3.     Parsley
4.     Watercress
5.     Asparagus
6.     Brussels
7.     Spouts
8.     Green beans
9.     Green peas
10. Carrots.

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